propylparabens
What are the health concerns?
Endocrine disruption: Of greatest concern is that parabens are known to disrupt hormone function, an effect that is linked to increased risk of breast cancer and reproductive toxicity. Parabens mimic estrogen by binding to estrogen receptors on cells. They also increase the expression of genes usually regulated by estradiol (a natural form of estrogen); these genes cause human breast cancer cells to grow and multiply in cellular studies [9]. Parabens are also linked to cancer, reproductive toxicity, immunotoxicity, neurotoxicity and skin irritation [10]. Since parabens are used to kill bacteria in water-based solutions, they inherently have some toxicity to cells [11].
The Possible Dangers of Propylparaben
One of the main propylparaben dangers cited by dermatologists and skin care specialists is the chemical’s ability to mimic estrogen in the human body, causing an over-abundance of this hormone. Because hormones play such a vital role in the body by stimulating various biological processes, chemicals that mimic hormones can lead to a significant number of problems and pain from internal inflammation. When this happens, you may start gaining weight, retaining more fluids, and can even lead to cancer. Estrogen-related problems from propylparaben are especially detrimental to women who are pregnant or nursing, and are already facing wide hormonal fluctuations.
Propylparaben and Cancer
Quite a few studies have been conducted to see if a link exists between propylparaben and breast cancer, but most research has been inconclusive. While some experts believe there is a link, as parabens have been found in cancerous breast tissue, there is not enough evidence to make a solid case. If you have a history of breast cancer (or any other cancer) in your family, or are concerned about the possible link between propylparaben and estrogen toxicity, consult your doctor or skin care professional about using this ingredient safely.
